GPCRmd

GPCRmd dataset

Class A (Rhodopsin)

Aminergic receptors

5-Hydroxytryptamine receptors

5-HT_1A receptor

5-HT_1B receptor

4IAQ

Apoform: 5-hydroxytryptamine receptor 1B (ID 85)

4IAR

Apoform: 5-hydroxytryptamine receptor 1B (ID 87)

Complex: 5-hydroxytryptamine receptor 1B in complex with ergotamine (ID 90)

5V54

Apoform: 5-hydroxytryptamine receptor 1b (apoform) (ID 908)

Complex: 5-hydroxytryptamine receptor 1b in complex with RLJFTICUTYVZDG-SFHVURJKSA-N (ID 909)

5-HT_1D receptor

5-HT_1E receptor

5-HT_1F receptor

5-HT_2A receptor

6A93

Apoform: 5-hydroxytryptamine receptor 2a (apoform) (ID 848)

Complex: 5-hydroxytryptamine receptor 2a in complex with RAPZEAPATHNIPO-UHFFFAOYSA-N (ID 849)

6A94

Apoform: 5-hydroxytryptamine receptor 2a (apoform) (ID 801)

Complex: 5-hydroxytryptamine receptor 2a in complex with HDOZVRUNCMBHFH-UHFFFAOYSA-N (ID 802)

5-HT_2B receptor

6DRX

Apoform: 5ht2b receptor (apoform) (ID 718)

Complex: 5ht2b receptor in complex with BKRGVLQUQGGVSM-KBXCAEBGSA-N (ID 719)

5TVN

Apoform: 5-HT2B receptor (ID 211)

Apoform: 5-HT2B receptor (ID 213)

Complex: 5-HT2B receptor in complex with Lysergide (ID 214)

Apoform: 5-HT2B receptor (ID 215)

Apoform: 5-HT2B receptor (ID 216)

Apoform: name 5-HT2B receptor (ID 217)

Apoform: chimera protein of human 5-hydroxytryptamine receptor 2b and e. coli soluble cytochrome b562 (apoform) (ID 846)

Complex: chimera protein of human 5-hydroxytryptamine receptor 2b and e. coli soluble cytochrome b562 in complex with VAYOSLLFUXYJDT-RDTXWAMCSA-N (ID 847)

4NC3

Apoform: chimera protein of human 5-hydroxytryptamine receptor 2b and e. coli soluble cytochrome b562 (apoform) (ID 819)

Complex: chimera protein of human 5-hydroxytryptamine receptor 2b and e. coli soluble cytochrome b562 in complex with Ergotamine (ID 820)

6DS0

Apoform: 5ht2b receptor (apoform) (ID 959)

Complex: 5ht2b receptor in complex with NJLHHCITDFZZSE-KRWDZBQOSA-N (ID 960)

6DRY

Apoform: 5ht2b receptor (apoform) (ID 918)

Complex: 5ht2b receptor in complex with UNBRKDKAWYKMIV-QWQRMKEZSA-N (ID 919)

4IB4

Complex: 5-hydroxytryptamine receptor 2B in complex with ergotamine (ID 94)

Apoform: 5-hydroxytryptamine receptor 2B (ID 92)

6DRZ

Apoform: 5ht2b receptor (apoform) (ID 811)

Complex: 5ht2b receptor in complex with KPJZHOPZRAFDTN-ZRGWGRIASA-N (ID 812)

5-HT_2C receptor

5-HT₄ receptor

5-HT_5A receptor

5-HT_5B receptor

5-HT₆ receptor

5-HT₇ receptor

Acetylcholine receptors (muscarinic)

M₁ receptor

5CXV

Apoform: Muscarinic acetylcholine receptor M1 (ID 154)

Complex: Muscarinic acetylcholine receptor M1 in complex with Tiotropium (ID 194)

M₂ receptor

5ZKB

Complex: muscarinic acetylcholine receptor m2 in complex with MZDYABXXPZNUCT-NRFANRHFSA-N (ID 1029)

Apoform: muscarinic acetylcholine receptor m2 (apoform) (ID 1028)

5ZK8

Complex: M2 muscarinic acetylcholine receptor in complex with NMS (ID 1096)

Apoform: muscarinic acetylcholine receptor m2 (apoform) (ID 797)

4MQT

Apoform: Muscarinic acetylcholine receptor M2 (ID 72)

5ZKC

Complex: M2 muscarinic acetylcholine receptor in complex with with NMS (ID 1126)

Apoform: muscarinic acetylcholine receptor m2 (apoform) (ID 968)

5ZK3

Apoform: muscarinic acetylcholine receptor m2 (apoform) (ID 989)

Complex: muscarinic acetylcholine receptor m2 in complex with HGMITUYOCPPQLE-IBGZPJMESA-N (ID 990)

4MQS

Apoform: Muscarinic acetylcholine receptor M2 (ID 68)

Complex: Muscarinic acetylcholine receptor M2 in complex with iperoxo (ID 69)

3UON

Complex: Muscarinic acetylcholine receptor M2 in complex with QUINUCLIDINYL BENZILATE (ID 112)

Apoform: Muscarinic acetylcholine receptor M2 (ID 111)

5YC8

Complex: M2 muscarinic acetylcholine receptor bound with NMS (ID 1127)

M₃ receptor

5ZHP

Complex: M3 muscarinic acetylcholine receptor in complex with a selective antagonist (ID 1125)

Apoform: muscarinic acetylcholine receptor m3 (apoform) (ID 947)

4U16

Apoform: Muscarinic acetylcholine receptor M3 (ID 175)

Complex: Muscarinic acetylcholine receptor M3 in complex with Paminereg (ID 176)

4U15

Apoform: Muscarinic acetylcholine receptor M3 (ID 93)

Complex: Muscarinic acetylcholine receptor M3 in complex with Tiotropium (ID 174)

M₄ receptor

5DSG

Apoform: Muscarinic acetylcholine receptor M4 (ID 157)

Complex: Muscarinic acetylcholine receptor M4 in complex with Tiotropium (ID 173)

6KP6

Apoform: muscarinic acetylcholine receptor m4 (apoform) (ID 983)

M₅ receptor

6OL9

Complex: M5 muscarinic acetylcholine receptor in complex with tiotropium (ID 1094)

Apoform: muscarinic acetylcholine receptor m5 (apoform) (ID 973)

Adrenoceptors

α_1A-adrenoceptor

α_1B-adrenoceptor

α_1D-adrenoceptor

α_2A-adrenoceptor

α_2B-adrenoceptor

α_2C-adrenoceptor

β₁-adrenoceptor

5A8E

Apoform: Beta-1 adrenergic receptor (ID 147)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 148)

Complex: Beta-1 adrenergic receptor in complex with XTK (ID 149)

Complex: Partially thermostabilized Beta-1 adrenergic receptor in complex with XTK (ID 150)

2Y03

Apoform: Beta-1 adrenergic receptor (ID 23)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 24)

Complex: Beta-1 adrenergic receptor in complex with levisoprenaline (ID 25)

Complex: Partially thermostabilized Beta-1 adrenergic receptor in complex with levisoprenaline (ID 26)

2YCZ

Apoform: beta-1 adrenergic receptor (apoform) (ID 785)

Complex: beta-1 adrenergic receptor in complex with JBLUMBNIBNHRSO-JTQLQIEISA-N (ID 786)

2Y02

Complex: Beta-1 adrenergic receptor in complex with carmoterol (ID 19)

Complex: Partially thermostabilized Beta-1 adrenergic receptor in complex with carmoterol (ID 20)

Apoform: Beta-1 adrenergic receptor (ID 17)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 18)

3ZPQ

Apoform: Beta-1 adrenergic receptor (ID 131)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 132)

Complex: Beta-1 adrenergic receptor in complex with 4-(1-Piperazinyl)-1H-indole (ID 133)

Complex: Partially thermostabilized Beta-1 adrenergic receptor in complex with 4-(1-Piperazinyl)-1H-indole (ID 134)

2Y04

Apoform: Beta-1 adrenergic receptor (ID 27)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 28)

Complex: Beta-1 adrenergic receptor in complex with levalbuterol (ID 29)

Complex: Beta-1 adrenergic receptor in complex with levalbuterol (ID 55)

5F8U

Apoform: beta-1 adrenergic receptor (apoform) (ID 728)

Complex: beta-1 adrenergic receptor in complex with CQEFAUFOQSCRMZ-LBPRGKRZSA-N (ID 729)

2Y00

Apoform: Beta-1 adrenergic receptor (ID 13)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 14)

Complex: Beta-1 adrenergic receptor in complex with R-dobutamine (ID 15)

Complex: Partially thermostabilized Beta-1 adrenergic receptor in complex with (R)-dobutamine (ID 16)

4AMJ

Apoform: Beta-1 adrenergic receptor (ID 141)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 142)

Complex: Beta-1 adrenergic receptor (ID 167)

Complex: Partially thermostabilized Beta-1 adrenergic receptor in complex with (S)-Carvedilol (ID 195)

4GPO

Apoform: beta-1 adrenergic receptor (apoform) (ID 961)

4BVN

Complex: Partially thermostabilized Beta-1 adrenergic receptor (ID 58)

Apoform: Beta-1 adrenergic receptor (ID 143)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 144)

4AMI

Apoform: Beta-1 adrenergic receptor (ID 138)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 139)

Complex: Partially thermostabilized Beta-1 adrenergic receptor (ID 140)

3ZPR

Apoform: Beta-1 adrenergic receptor (ID 135)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 136)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 137)

2YCW

Apoform: Beta-1 adrenergic receptor (ID 56)

Complex: Beta-1 adrenergic receptor complex with carazolol (ID 57)

Apoform: Partially thermostabilized Beta-1 adrenergic receptor (ID 64)

β₂-adrenoceptor

6PRZ

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 979)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with PAZJSJFMUHDSTF-AWEZNQCLSA-N (ID 980)

3PDS

Apoform: Beta-2 adrenergic receptor (ID 107)

2RH1

Apoform: Beta-2 adrenergic receptor (ID 11)

4QKX

Apoform: Beta-2 adrenergic receptor (ID 82)

3NY8

Complex: Beta-2 adrenergic receptor in complex with ICI-118551 (ID 123)

Apoform: Beta-2 adrenergic receptor (ID 88)

6PS5

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 751)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with 1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL (ID 752)

6PS3

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 926)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with OGHNVEJMJSYVRP-KRWDZBQOSA-N (ID 927)

4LDL

Apoform: Beta-2 adrenergic receptor (ID 114)

Complex: Beta-2 adrenergic receptor in complex with CHEMBL1160696 (ID 115)

4LDO

Apoform: Beta-2 adrenergic receptor (ID 116)

Complex: Beta-2 adrenergic receptor in complex with epinephrine (ID 117)

5D6L

Apoform: beta-2 adrenergic receptor (apoform) (ID 962)

Complex: beta-2 adrenergic receptor in complex with BQXQGZPYHWWCEB-ZDUSSCGKSA-N (ID 963)

4LDE

Apoform: Beta-2 adrenergic receptor (ID 113)

Complex: Beta-2 adrenergic receptor in complex with 8-[(1r)-2-{[1,1-Dimethyl-2-(2-Methylphenyl)ethyl]amino... (ID 121)

6PS4

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 829)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with VFIDUCMKNJIJTO-XJKSGUPXSA-N (ID 830)

6PS0

Apoform: 6PS0 apoform (ID 684)

Complex: 6PS0 complex (ID 685)

6PS2

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 863)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with PAZJSJFMUHDSTF-AWEZNQCLSA-N (ID 864)

6PS6

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 951)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with BLJRIMJGRPQVNF-JTQLQIEISA-N (ID 952)

3NYA

Complex: Beta-2 adrenergic receptor in complex with (-)-Alprenolol (ID 124)

Apoform: Beta-2 adrenergic receptor (ID 100)

5JQH

Apoform: Beta-2 adrenergic receptor (ID 159)

Complex: Beta-2 adrenergic receptor in complex with (S)-carozol (ID 160)

5X7D

Apoform: chimera protein of beta-2 adrenergic receptor and lysozyme (apoform) (ID 769)

Complex: chimera protein of beta-2 adrenergic receptor and lysozyme in complex with BQXQGZPYHWWCEB-ZDUSSCGKSA-N (ID 770)

3D4S

Apoform: Beta-2 adrenergic receptor (ID 65)

Complex: Beta-2 adrenergic receptor in complex with Aquanil (ID 83)

3NY9

Apoform: Beta-2 adrenergic receptor (ID 96)

Complex: Beta-2 adrenergic receptor in complex with CHEMBL1233771 (ID 99)

4GBR

Apoform: beta-2 adrenergic receptor (apoform) (ID 970)

Complex: beta-2 adrenergic receptor in complex with BQXQGZPYHWWCEB-ZDUSSCGKSA-N (ID 971)

6PS1

Apoform: fusion protein of beta-2 adrenergic receptor and t4 lysozyme (apoform) (ID 763)

Complex: fusion protein of beta-2 adrenergic receptor and t4 lysozyme in complex with BLJRIMJGRPQVNF-JTQLQIEISA-N (ID 764)

6OBA

Complex: beta-2 adrenergic receptor in complex with 6-bromo-N~2~-phenylquinazoline-2,4-diamine (ID 1130)

Apoform: beta-2 adrenergic receptor (apoform) (ID 1003)

β₃-adrenoceptor

Dopamine receptors

D₁ receptor

D₂ receptor

6LUQ

Apoform: chimera of d(2) dopamine receptor and endolysin (apoform) (ID 838)

Complex: chimera of d(2) dopamine receptor and endolysin in complex with LNEPOXFFQSENCJ-UHFFFAOYSA-N (ID 839)

6CM4

Apoform: d(2) dopamine receptor (apoform) (ID 924)

Complex: d(2) dopamine receptor in complex with RAPZEAPATHNIPO-UHFFFAOYSA-N (ID 925)

D₃ receptor

3PBL

Apoform: D(3) dopamine receptor (ID 105)

Complex: D(3) dopamine receptor in complex with Eticlopride (ID 106)

D₄ receptor

5WIV

Apoform: d(4) dopamine receptor (apoform) (ID 831)

Complex: d(4) dopamine receptor in complex with Nemonapride (ID 832)

5WIU

Apoform: d(4) dopamine receptor (apoform) (ID 1005)

Complex: d(4) dopamine receptor in complex with Nemonapride (ID 1006)

D₅ receptor

Histamine receptors

H₁ receptor

3RZE

Apoform: Histamine H1 receptor (ID 108)

Complex: Histamine H1 receptor in complex with doxepin (ID 109)

Complex: Histamine H1 receptor in complex with Z-doxepin (ID 126)

H₂ receptor

H₃ receptor

H₄ receptor

Trace amine receptors

Peptide receptors

Angiotensin receptors

AT₁ receptor

4ZUD

Complex: Type-1 angiotensin II receptor with olmesartan (ID 120)

Complex: Type-1 angiotensin II receptor (ID 146)

Apoform: Type-1 angiotensin II receptor (ID 189)

Complex: Type-1 angiotensin II receptor in complex with olmesartan (ID 190)

4YAY

Apoform: Type-1 angiotensin II receptor (ID 166)

6DO1

Complex: angiotensin II type 1 receptor (ID 218)

Complex: angiotensin II type 1 receptor in complex with modified ANG II (ID 219)

Complex: angiotensin II type 1 receptor incomplex with TRV023 (ID 220)

AT₂ receptor

5UNF

Apoform: chimera protein of type-2 angiotensin ii receptor and soluble cytochrome b562 (apoform) (ID 916)

Complex: chimera protein of type-2 angiotensin ii receptor and soluble cytochrome b562 in complex with KDPHUUTUDFDLBT-UHFFFAOYSA-N (ID 917)

5UNH

Apoform: type-2 angiotensin ii receptor (apoform) (ID 939)

Complex: type-2 angiotensin ii receptor in complex with SYDVEZUPFQXMSM-UHFFFAOYSA-N (ID 940)

5UNG

Apoform: chimera protein of type-2 angiotensin ii receptor and soluble cytochrome b562 (apoform) (ID 890)

Complex: chimera protein of type-2 angiotensin ii receptor and soluble cytochrome b562 in complex with KDPHUUTUDFDLBT-UHFFFAOYSA-N (ID 891)

Apelin receptors

apelin receptor

5VBL

Apoform: Apelin receptor (apoform) (ID 1063)

Complex: Apelin receptor in complex with agonist peptide (ID 1062)

Bombesin receptors

Bradykinin receptors

Cholecystokinin receptors

Complement peptide receptors

C3a receptor

C5a₁ receptor

5O9H

Apoform: c5a anaphylatoxin chemotactic receptor 1 (apoform) (ID 920)

Complex: c5a anaphylatoxin chemotactic receptor 1 in complex with ITACCRHKSPSKKL-UHFFFAOYSA-N (ID 921)

C5a₂ receptor

Endothelin receptors

ET_A receptor

ET_B receptor

5GLH

Complex: Endothelin B receptor in complex with Endothelin-1 (ID 168)

Apoform: Endothelin B receptor (ID 158)

5XPR

Apoform: endothelin b receptor (apoform) (ID 886)

Complex: endothelin b receptor in complex with GJPICJJJRGTNOD-UHFFFAOYSA-N (ID 887)

6K1Q

Apoform: endothelin b receptor (apoform) (ID 787)

Complex: endothelin b receptor in complex with UZDORQWMYRRLQV-JHOUSYSJSA-N (ID 788)

6IGL

Apoform: Endothelin receptor type B (apoform) (ID 1059)

Complex: Endothelin receptor type B in complex with IRL 1620 (ID 1064)

6LRY

Apoform: endothelin receptor type b (apoform) (ID 996)

Complex: endothelin receptor type b in complex with sarafotoxin-b (ID 997)

5GLI

Apoform: endothelin receptor subtype-b (apoform) (ID 837)

5X93

Apoform: endothelin b receptor (apoform) (ID 964)

Complex: endothelin b receptor in complex with MTNFANNLCUMCNB-UHFFFAOYSA-N (ID 965)

6IGK

Apoform: endothelin receptor type b (apoform) (ID 1015)

Complex: endothelin receptor type b in complex with endothelin-3 (ID 1016)

Formylpeptide receptors

Galanin receptors

Ghrelin receptors

Gonadotrophin-releasing hormone receptors

Kisspeptin receptors

Melanin-concentrating hormone

Melanocortin receptors

Motilin receptors

Neuromedin U receptors

Neuropeptide FF/neuropeptide AF receptors

Neuropeptide S receptors

Neuropeptide W/neuropeptide B receptors

Neuropeptide Y receptors

Y₁ receptor

5ZBH

Apoform: neuropeptide y receptor type 1 (apoform) (ID 904)

Complex: neuropeptide y receptor type 1 in complex with WMYSXJSJXZFODY-UHFFFAOYSA-N (ID 905)

5ZBQ

Complex: neuropeptide y receptor type 1 in complex with VQHNWOOVOKYJNL-HHHXNRCGSA-N (ID 1040)

Apoform: neuropeptide y receptor type 1 (apoform) (ID 700)

Y₂ receptor

Y₄ receptor

Y₅ receptor

y₆ receptor

Neurotensin receptors

NTS₁ receptor

4XES

Apoform: neurotensin receptor type 1 (apoform) (ID 767)

Complex: neurotensin receptor type 1 in complex with neurotensin/neuromedin n (ID 768)

4XEE

Apoform: Neurotensin receptor type 1 (ID 177)

Complex: Neurotensin receptor type 1 in complex with Neurotensin (ID 178)

4BUO

Apoform: neurotensin receptor type 1 (apoform) (ID 880)

Complex: neurotensin receptor type 1 in complex with GLYCINE (ID 881)

5T04

Apoform: neurotensin receptor type 1 (apoform) (ID 722)

Complex: neurotensin receptor type 1 in complex with arg-arg-pro-tyr-ile-leu (ID 723)

4GRV

Apoform: Neurotensin receptor type 1 (ID 66)

Complex: Neurotensin receptor type 1 in complex with neurotensin (ID 71)

NTS₂ receptor

Opioid receptors

δ receptor

4N6H

Complex: Delta-type opioid receptor in complex with Naltrindole (ID 145)

Apoform: Delta-type opioid receptor (ID 73)

4RWD

Apoform: Delta-type opioid receptor (ID 84)

4EJ4

Apoform: delta-type opioid receptor (apoform) (ID 724)

Complex: delta-type opioid receptor in complex with WIYUZYBFCWCCQJ-IFKAHUTRSA-N (ID 725)

κ receptor

4DJH

Apoform: Kappa-type opioid receptor (ID 59)

Complex: Kappa-type opioid receptor in complex with JDTic (ID 60)

μ receptor

5C1M

Complex: Mu-type opioid receptor in complex with BU72 (ID 169)

Apoform: Mu-type opioid receptor (ID 151)

4DKL

Apoform: Mu-type opioid receptor (ID 61)

NOP receptor

4EA3

Apoform: Nociceptin receptor (ID 62)

Complex: Nociceptin receptor in complex with 1-benzyl-N-[3-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-y... (ID 70)

5DHG

Apoform: Nociceptin receptor (ID 156)

5DHH

Apoform: Nociceptin receptor (ID 155)

Orexin receptors

OX₁ receptor

6TQ9

Apoform: orexin receptor type 1 (apoform) (ID 833)

Complex: orexin receptor type 1 in complex with JTARFZSNUAGHRB-UHFFFAOYSA-N (ID 834)

6TP4

Apoform: orexin receptor type 1 (apoform) (ID 759)

Complex: orexin receptor type 1 in complex with NHPQGZOBHSVTAQ-IBGZPJMESA-N (ID 760)

6TOD

Apoform: orexin receptor type 1 (apoform) (ID 914)

Complex: orexin receptor type 1 in complex with KJPHTXTWFHVJIG-UHFFFAOYSA-N (ID 915)

4ZJ8

Apoform: Orexin receptor type 1 (ID 186)

Complex: Orexin receptor type 1 in complex with suvorexant (ID 187)

6TOS

Apoform: orexin receptor type 1 (apoform) (ID 821)

Complex: orexin receptor type 1 in complex with TWCRHJLMMAYSTE-ZFWWWQNUSA-N (ID 822)

6TOT

Apoform: orexin receptor type 1 (apoform) (ID 874)

Complex: orexin receptor type 1 in complex with MUGXRYIUWFITCP-PGRDOPGGSA-N (ID 875)

6TQ6

Apoform: orexin receptor type 1 (apoform) (ID 859)

Complex: orexin receptor type 1 in complex with LWKUASRJTUZHSJ-UHFFFAOYSA-N (ID 860)

6TP3

Apoform: orexin receptor type 1 (apoform) (ID 758)

6TO7

Apoform: orexin receptor type 1 (apoform) (ID 935)

Complex: orexin receptor type 1 in complex with JYTNQNCOQXFQPK-MRXNPFEDSA-N (ID 936)

4ZJC

Complex: Orexin receptor type 1 in complex with sb-674042 (ID 188)

6TQ4

Apoform: orexin receptor type 1 (apoform) (ID 966)

Complex: orexin receptor type 1 in complex with KIKWLYIDCILHAP-UHFFFAOYSA-N (ID 967)

6TP6

Apoform: orexin receptor type 1 (apoform) (ID 869)

Complex: orexin receptor type 1 in complex with NPFDWHQSDBWQLH-QZTJIDSGSA-N (ID 870)

6TQ7

Apoform: orexin receptor type 1 (apoform) (ID 736)

Complex: orexin receptor type 1 in complex with AKMNUCBQGHFICM-UHFFFAOYSA-N (ID 737)

OX₂ receptor

5WQC

Apoform: orexin receptor type 2 (apoform) (ID 844)

Complex: orexin receptor type 2 in complex with KJPHTXTWFHVJIG-UHFFFAOYSA-N (ID 845)

4S0V

Complex: Orexin receptor type 2 in complex with Suvorexant (ID 172)

Apoform: Orexin receptor type 2 (ID 91)

6TPJ

Apoform: hypocretin receptor-2 (apoform) (ID 744)

Complex: hypocretin receptor-2 in complex with JYTNQNCOQXFQPK-MRXNPFEDSA-N (ID 745)

6TPG

Apoform: hypocretin receptor-2 (apoform) (ID 865)

Complex: hypocretin receptor-2 in complex with KJPHTXTWFHVJIG-UHFFFAOYSA-N (ID 866)

6TPN

Apoform: orexin receptor type 2 (apoform) (ID 902)

Complex: orexin receptor type 2 in complex with SUQZCEUKWPKXEE-UHFFFAOYSA-N (ID 903)

5WS3

Apoform: orexin receptor type 2 (apoform) (ID 726)

Complex: orexin receptor type 2 in complex with KJPHTXTWFHVJIG-UHFFFAOYSA-N (ID 727)

Peptide P518 receptors

Prolactin-releasing peptide receptors

Proteinase-activated receptors

PAR1

3VW7

Apoform: Proteinase-activated receptor 1 (ID 128)

Complex: Proteinase-activated receptor 1 (ID 129)

Complex: Proteinase-activated receptor 1 in complex with Vorapaxar (ID 130)

PAR2

5NDD

Apoform: proteinase-activated receptor 2 (apoform) (ID 977)

Complex: proteinase-activated receptor 2 in complex with IDFPQEHZYBXIFO-LBPRGKRZSA-N (ID 978)

5NDZ

Apoform: proteinase-activated receptor 2 (apoform) (ID 1018)

Complex: proteinase-activated receptor 2 in complex with FJAOGFGHTPYADT-SFHVURJKSA-N (ID 1019)

PAR3

PAR4

Relaxin family peptide receptors

Somatostatin receptors

Tachykinin receptors

NK₁ receptor

6HLP

Apoform: substance-p receptor (apoform) (ID 937)

Complex: substance-p receptor in complex with WAXQNWCZJDTGBU-UHFFFAOYSA-N (ID 938)

6HLO

Apoform: substance-p receptor (apoform) (ID 730)

Complex: substance-p receptor in complex with ATALOFNDEOCMKK-OITMNORJSA-N (ID 731)

6J21

Apoform: substance-p receptor (apoform) (ID 781)

Complex: substance-p receptor in complex with ATALOFNDEOCMKK-OITMNORJSA-N (ID 782)

6HLL

Apoform: substance-p receptor (apoform) (ID 850)

Complex: substance-p receptor in complex with DTQNEFOKTXXQKV-HKUYNNGSSA-N (ID 851)

6J20

Apoform: substance-p receptor (apoform) (ID 910)

Complex: substance-p receptor in complex with ATALOFNDEOCMKK-OITMNORJSA-N (ID 911)

6E59

Apoform: substance-p receptor chimera (apoform) (ID 855)

Complex: substance-p receptor chimera in complex with USRYEHHMJIRICK-ZNZBMKLDSA-N (ID 856)

NK₂ receptor

NK₃ receptor

Thyrotropin-releasing hormone receptors

Urotensin receptors

Vasopressin and oxytocin receptors

Protein receptors

Chemerin receptor

Chemokine receptors

CCR1

CCR2

6GPX

Apoform: c-c chemokine receptor type 2 (apoform) (ID 799)

Complex: c-c chemokine receptor type 2 in complex with MTMDXAIUENDNDL-RJSMDTJLSA-O (ID 800)

6GPS

Apoform: c-c chemokine receptor type 2 (apoform) (ID 708)

Complex: c-c chemokine receptor type 2 in complex with MTMDXAIUENDNDL-RJSMDTJLSA-O (ID 709)

5T1A

Apoform: chimera protein of cc chemokine receptor type 2 isoform b and t4-lysozyme (apoform) (ID 734)

Complex: chimera protein of cc chemokine receptor type 2 isoform b and t4-lysozyme in complex with VQNLJXWZGVRLBA-MRXNPFEDSA-N (ID 735)

CCR3

CCR4

CCR5

4MBS

Complex: C-C chemokine receptor type 5 in complex with maravirocum (ID 67)

Apoform: C-C chemokine receptor type 5 (ID 118)

Complex: C-C chemokine receptor type 5 in complex with maravirocum (ID 119)

6AKY

Complex: Chemokine Receptor CCR5 in complex with compound 34 (ID 1124)

Apoform: c-c chemokine receptor type 5 (apoform) (ID 941)

5UIW

Apoform: c-c chemokine receptor type 5 (apoform) (ID 898)

Complex: c-c chemokine receptor type 5 in complex with c-c motif chemokine 5 (ID 899)

6AKX

Complex: Chemokine Receptor CCR5 in complex with compound 21 (ID 1095)

Apoform: c-c chemokine receptor type 5 (apoform) (ID 779)

CCR6

CCR7

CCR8

CCR9

CCR10

CXCR1

CXCR2

CXCR3

CXCR4

4RWS

Complex: C-X-C chemokine receptor type 4 in complex with vMIP-II W5C mutant. (ID 86)

Complex: C-X-C chemokine receptor type 4 in complex with vMIP-II W5C mutant. (ID 89)

Apoform: C-X-C chemokine receptor type 4 (ID 98)

3ODU

Complex: C-X-C chemokine receptor type 4 in complex with IT1t (ID 102)

Complex: C-X-C chemokine receptor type 4 in complex with 1t (ID 103)

Apoform: C-X-C chemokine receptor type 4 (ID 101)

3OE0

Apoform: C-X-C chemokine receptor type 4 (ID 104)

CXCR5

CXCR6

CX₃CR1

XCR1

ACKR1

ACKR2

ACKR3

ACKR4

CCRL2

Glycoprotein hormone receptors

Prokineticin receptors

Lipid receptors

Free fatty acid receptors

FFA1 receptor

5KW2

Apoform: free fatty acid receptor 1 (apoform) (ID 765)

Complex: free fatty acid receptor 1 in complex with RJZJYKXHTPUHAO-HKBQPEDESA-N (ID 766)

5TZR

Apoform: free fatty acid receptor 1 (apoform) (ID 793)

Complex: free fatty acid receptor 1 in complex with CODQKEMYZZKQAE-QPVYNBJUSA-N (ID 794)

5TZY

Apoform: free fatty acid receptor 1 (apoform) (ID 928)

Complex: free fatty acid receptor 1 in complex with ADYYYLTWZYYGNX-LJYIQKJHSA-N (ID 929)

4PHU

Apoform: Free fatty acid receptor 1 (ID 75)

Complex: Free fatty acid receptor 1 in complex with TAK-875 (ID 76)

FFA2 receptor

FFA3 receptor

FFA4 receptor

GPR42

Leukotriene receptors

BLT₁ receptor

5X33

Apoform: ltb4 receptor (apoform) (ID 957)

Complex: ltb4 receptor in complex with MBLJFKQACMILLC-UHFFFAOYSA-N (ID 958)

BLT₂ receptor

CysLT₁ receptor

6RZ4

Apoform: cysteinyl leukotriene receptor 1 (apoform) (ID 738)

Complex: cysteinyl leukotriene receptor 1 in complex with pranlukast (ID 739)

6RZ5

Apoform: cysteinyl leukotriene receptor 1 (apoform) (ID 861)

Complex: cysteinyl leukotriene receptor 1 in complex with zafirlukast (ID 862)

CysLT₂ receptor

6RZ6

Apoform: cysteinyl leukotriene receptor 2 (apoform) (ID 825)

Complex: cysteinyl leukotriene receptor 2 in complex with JCUVQOJHURMRKB-SANMLTNESA-N (ID 826)

6RZ8

Apoform: cysteinyl leukotriene receptor 2 (apoform) (ID 789)

Complex: cysteinyl leukotriene receptor 2 in complex with FRDYFKGGRISGHW-VWLOTQADSA-N (ID 790)

6RZ7

Apoform: cysteinyl leukotriene receptor 2 (apoform) (ID 805)

Complex: cysteinyl leukotriene receptor 2 in complex with JCUVQOJHURMRKB-SANMLTNESA-N (ID 806)

6RZ9

Apoform: cysteinyl leukotriene receptor 2 (apoform) (ID 690)

Complex: cysteinyl leukotriene receptor 2 in complex with AXUGAYNPVSAVSA-MHZLTWQESA-N (ID 691)

OXE receptor

Lysophospholipid (LPA) receptors

LPA₁ receptor

4Z36

Complex: Lysophosphatidic acid receptor 1 in complex withi ono-3080573 (ID 185)

4Z35

Apoform: Lysophosphatidic acid receptor 1 (ID 184)

4Z34

Apoform: Lysophosphatidic acid receptor 1 (ID 171)

Complex: Lysophosphatidic acid receptor 1 in complex with ono9780307 (ID 183)

LPA₂ receptor

LPA₃ receptor

LPA₄ receptor

LPA₅ receptor

LPA₆ receptor

5XSZ

Apoform: lysophosphatidic acid receptor 6a (apoform) (ID 871)

Lysophospholipid (S1P) receptors

S1P₁ receptor

3V2Y

Apoform: Sphingosine 1-phosphate receptor 1 (ID 63)

Complex: Sphingosine 1-phosphate receptor 1 in complex with W146 (ID 127)

S1P₂ receptor

S1P₃ receptor

S1P₄ receptor

S1P₅ receptor

Cannabinoid receptors

CB₁ receptor

6KQI

Complex: cannabinoid receptor 1 in complex with AHFZDNYNXFMRFQ-UHFFFAOYSA-N (ID 1002)

5U09

Complex: Cannabinoid receptor 1 in complex with taranabant (ID 22)

Apoform: Cannabinoid receptor 1 (ID 163)

Complex: Cannabinoid receptor 1 in complex with Taranabant (ID 164)

5XRA

Apoform: cannabinoid receptor 1 (apoform) (ID 896)

Complex: cannabinoid receptor 1 in complex with SZDVFUZKFPGYEK-WOJBJXKFSA-N (ID 897)

5XR8

Apoform: cannabinoid receptor 1 (apoform) (ID 852)

5TGZ

Apoform: Cannabinoid receptor 1 (ID 162)

CB₂ receptor

6KPC

Apoform: cannabinoid receptor 2 (apoform) (ID 955)

Complex: cannabinoid receptor 2 in complex with JCIYJYHFBBXSBF-HMXCVIKNSA-N (ID 956)

GPR18, GPR55 and GPR119

Platelet-activating factor receptors

PAF receptor

5ZKQ

Apoform: platelet-activating factor receptor (apoform) (ID 694)

Complex: platelet-activating factor receptor in complex with GDLNHSUSOZEAOR-UHFFFAOYSA-N (ID 695)

5ZKP

Apoform: platelet-activating factor receptor (apoform) (ID 1024)

Complex: platelet-activating factor receptor in complex with VVBFISAUNSXQGZ-UHFFFAOYSA-N (ID 1025)

Prostanoid receptors

DP₁ receptor

DP₂ receptor

6D27

Apoform: prostaglandin d2 receptor 2 (apoform) (ID 884)

Complex: prostaglandin d2 receptor 2 in complex with CANCTKXGRVNXFP-OAHLLOKOSA-N (ID 885)

6D26

Apoform: prostaglandin d2 receptor 2 (apoform) (ID 984)

Complex: prostaglandin d2 receptor 2 in complex with fevipiprant (ID 985)

EP₁ receptor

EP₂ receptor

EP₃ receptor

6M9T

Apoform: prostaglandin e2 receptor ep3 subtype (apoform) (ID 748)

Complex: prostaglandin e2 receptor ep3 subtype in complex with CNWGPXZGIIOYDL-AGRNYGATSA-N (ID 749)

6AK3

Apoform: prostaglandin e2 receptor ep3 subtype (apoform) (ID 1026)

Complex: prostaglandin e2 receptor ep3 subtype in complex with XEYBRNLFEZDVAW-ARSRFYASSA-N (ID 1027)

EP₄ receptor

FP receptor

IP receptor

TP receptor

Melatonin receptors

Melatonin

MT₁ receptor

6ME2

Apoform: chimera protein of melatonin receptor type 1a and glga glycogen synthase (apoform) (ID 712)

Complex: chimera protein of melatonin receptor type 1a and glga glycogen synthase in complex with YLXDSYKOBKBWJQ-LBPRGKRZSA-N (ID 713)

6ME3

Apoform: chimera protein of melatonin receptor type 1a and glga glycogen synthase (apoform) (ID 692)

Complex: chimera protein of melatonin receptor type 1a and glga glycogen synthase in complex with OFCLARYYBGKCHN-UHFFFAOYSA-N (ID 693)

6ME5

Apoform: chimera protein of melatonin receptor type 1a and glga glycogen synthase (apoform) (ID 807)

Complex: chimera protein of melatonin receptor type 1a and glga glycogen synthase in complex with ~{N}-[2-(7-methoxynaphthalen-1-yl)ethyl]ethanamide (ID 808)

6ME4

Apoform: chimera protein of melatonin receptor type 1a and glga glycogen synthase (apoform) (ID 803)

Complex: chimera protein of melatonin receptor type 1a and glga glycogen synthase in complex with FJDDSMSDZHURBJ-UHFFFAOYSA-N (ID 804)

6PS8

Apoform: fusion protein of melatonin receptor type 1a and glga glycogen synthase (apoform) (ID 1007)

Complex: fusion protein of melatonin receptor type 1a and glga glycogen synthase in complex with OFCLARYYBGKCHN-UHFFFAOYSA-N (ID 1008)

MT₂ receptor

6ME6

Apoform: melatonin receptor type 1b (apoform) (ID 795)

Complex: melatonin receptor type 1b in complex with OFCLARYYBGKCHN-UHFFFAOYSA-N (ID 796)

6ME8

Apoform: melatonin receptor type 1b (apoform) (ID 945)

Complex: melatonin receptor type 1b in complex with OFCLARYYBGKCHN-UHFFFAOYSA-N (ID 946)

6ME9

Apoform: melatonin receptor type 1b (apoform) (ID 817)

Complex: melatonin receptor type 1b in complex with YLXDSYKOBKBWJQ-LBPRGKRZSA-N (ID 818)

6ME7

Apoform: melatonin receptor type 1b (apoform) (ID 993)

Complex: melatonin receptor type 1b in complex with OFCLARYYBGKCHN-UHFFFAOYSA-N (ID 994)

Nucleotide receptors

Adenosine receptors

A₁ receptor

5N2S

Complex: A1 receptor in complex with PSB36 (ID 1097)

Apoform: adenosine receptor a1 (apoform) (ID 775)

5UEN

Apoform: Adenosine receptor A1 (ID 21)

Apoform: Adenosine receptor A1 (ID 165)

A_2A receptor

5WF5

Apoform: human a2a adenosine receptor t4l chimera (apoform) (ID 1049)

Complex: human a2a adenosine receptor t4l chimera in complex with ZOTHAEBAWXWVID-HXEFRTELSA-N (ID 687)

6ZDR

Apoform: adenosine receptor a2a (apoform) (ID 1032)

Complex: adenosine receptor a2a in complex with FVMKJEVPLWCLMC-UHFFFAOYSA-N (ID 1033)

5IU8

Apoform: Adenosine receptor A2a (ID 52)

2YDO

Apoform: Adenosine receptor A2a (ID 30)

Complex: Adenosine receptor A2a in complex with adenosine (ID 31)

5OLZ

Apoform: adenosine receptor a2a (apoform) (ID 813)

Complex: adenosine receptor a2a in complex with ZHUZHTHIEMXLRA-UHFFFAOYSA-N (ID 814)

5IUA

Apoform: Adenosine receptor A2a (ID 53)

5K2A

Apoform: adenosine receptor a2a/soluble cytochrome b562 chimera (apoform) (ID 1020)

Complex: adenosine receptor a2a/soluble cytochrome b562 chimera in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 1021)

3QAK

Apoform: Adenosine receptor A2a (ID 34)

6AQF

Apoform: adenosine receptor a2a (apoform) (ID 753)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 754)

6JZH

Apoform: adenosine receptor a2a (apoform) (ID 1000)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 1001)

5UIG

Apoform: adenosine receptor a2a (apoform) (ID 773)

Complex: adenosine receptor a2a in complex with UJHUYWLZLDBDSR-UHFFFAOYSA-N (ID 774)

5NM2

Apoform: adenosine receptor a2a (apoform) (ID 783)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 784)

5OLV

Complex: adenosine receptor a2a in complex with KEUJAGGJGBWRFC-UHFFFAOYSA-N (ID 1017)

4UHR

Apoform: Adenosine receptor A2a (ID 45)

Complex: Adenosine receptor A2a in complex CGS-21680 (ID 46)

5OLO

Apoform: adenosine receptor a2a (apoform) (ID 975)

Complex: adenosine receptor a2a in complex with XNBRWUQWSKXMPW-UHFFFAOYSA-N (ID 976)

5IU7

Apoform: Adenosine receptor A2a (ID 51)

5VRA

Apoform: adenosine receptor a2a (apoform) (ID 1011)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 1012)

5MZJ

Complex: A2A adenosine receptor in complex with theophylline (ID 1098)

Apoform: adenosine receptor a2a (apoform) (ID 995)

5JTB

Apoform: adenosine receptor a2a (apoform) (ID 696)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 697)

2YDV

Apoform: Adenosine receptor A2a (ID 32)

Complex: Adenosine receptor A2a in complex with NECA (ID 33)

5NM4

Apoform: adenosine receptor a2a (apoform) (ID 953)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 954)

5UVI

Apoform: adenosine receptor a2a (apoform) (ID 835)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 836)

3UZA

Complex: Adenosine receptor A2a in complex with 6-(2,6-dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine (ID 40)

Apoform: Adenosine receptor A2a (ID 39)

5IUB

Apoform: Adenosine receptor A2a (ID 54)

5NLX

Apoform: adenosine receptor a2a (apoform) (ID 991)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 992)

5OLG

Apoform: adenosine receptor a2a (apoform) (ID 922)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 923)

3UZC

Complex: Adenosine receptor A2a in complex with 4-(3-Amino-5-phenyl-1,2,4-triazine-6-yl)-2-chlorophenol (ID 42)

Apoform: Adenosine receptor A2a (ID 41)

6MH8

Apoform: adenosine receptor a2a (apoform) (ID 981)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 982)

5OM4

Apoform: adenosine receptor a2a (apoform) (ID 714)

Complex: adenosine receptor a2a in complex with ZHUZHTHIEMXLRA-UHFFFAOYSA-N (ID 715)

5K2D

Apoform: adenosine receptor a2a/soluble cytochrome b562 chimera (apoform) (ID 949)

Complex: adenosine receptor a2a/soluble cytochrome b562 chimera in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 950)

6ZDV

Apoform: adenosine receptor a2a (apoform) (ID 827)

Complex: adenosine receptor a2a in complex with NVGMNXGIQPMJSN-UHFFFAOYSA-N (ID 828)

5WF6

Apoform: human a2a adenosine receptor t4l chimera (apoform) (ID 1009)

Complex: human a2a adenosine receptor t4l chimera in complex with ZOTHAEBAWXWVID-HXEFRTELSA-N (ID 1010)

5K2C

Apoform: adenosine receptor a2a/soluble cytochrome b562 chimera (apoform) (ID 998)

Complex: adenosine receptor a2a/soluble cytochrome b562 chimera in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 999)

5OLH

Apoform: adenosine receptor a2a (apoform) (ID 930)

Complex: adenosine receptor a2a in complex with HQSBCDPYXDGTCL-UHFFFAOYSA-N (ID 931)

6GT3

Apoform: adenosine receptor a2a (apoform) (ID 702)

Complex: adenosine receptor a2a in complex with NCWQLHHDGDXIJN-UHFFFAOYSA-N (ID 703)

3REY

Complex: Adenosine receptor A2a in complex with xanthine amine congener (ID 36)

Apoform: Adenosine receptor A2a (ID 35)

5MZP

Apoform: adenosine receptor a2a (apoform) (ID 987)

Complex: adenosine receptor a2a in complex with CAFFEINE (ID 988)

3RFM

Complex: Adenosine receptor A2a in complex with caffeine (ID 38)

Apoform: Adenosine receptor A2a (ID 37)

5OM1

Apoform: adenosine receptor a2a (apoform) (ID 857)

Complex: adenosine receptor a2a in complex with ZHUZHTHIEMXLRA-UHFFFAOYSA-N (ID 858)

4EIY

Apoform: Adenosine receptor A2a (ID 43)

Complex: Adenosine receptor A2a in complex with ZM241385 (ID 44)

6PS7

Apoform: adenosine receptor a2a (apoform) (ID 1013)

Complex: adenosine receptor a2a in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 1014)

5N2R

Complex: A2A adenosine receptor in complex with PSB36 (ID 1123)

Apoform: adenosine receptor a2a (apoform) (ID 906)

5K2B

Apoform: adenosine receptor a2a/soluble cytochrome b562 chimera (apoform) (ID 853)

Complex: adenosine receptor a2a/soluble cytochrome b562 chimera in complex with PWTBZOIUWZOPFT-UHFFFAOYSA-N (ID 854)

5IU4

Complex: Adenosine receptor A2a in complex with ZM241385 (ID 50)

Apoform: Adenosine receptor A2a (ID 49)

5G53

Apoform: Adenosine receptor A2a (ID 47)

Complex: Adenosine receptor A2a in complex with N-ethyl-5'-carboxamido adenosine (ID 48)

A_2B receptor

A₃ receptor

P2Y receptors

P2Y₁ receptor

4XNV

Apoform: P2Y purinoceptor 1 (ID 179)

Complex: P2Y purinoceptor 1 in complex with BPTU (ID 207)

4XNW

Apoform: P2Y purinoceptor 1 (ID 180)

Complex: P2Y purinoceptor 1 in complex with mrs-2500 (ID 181)

Complex: P2Y purinoceptor 1 in complex with mrs-2500 (ID 182)

P2Y₂ receptor

P2Y₄ receptor

P2Y₆ receptor

P2Y₁₁ receptor

P2Y₁₂ receptor

4PY0

Apoform: P2Y purinoceptor 12 (ID 79)

Complex: P2Y purinoceptor 12 in complex with 2-Mesatp (ID 80)

4NTJ

Apoform: p2y purinoceptor 12 (apoform) (ID 716)

Complex: p2y purinoceptor 12 in complex with NEMHKCNXXRQYRF-UHFFFAOYSA-N (ID 717)

4PXZ

Apoform: P2Y purinoceptor 12 (ID 77)

Complex: P2Y purinoceptor 12 in complex with Methylthio-adenosine diphosphate (ID 78)

P2Y₁₃ receptor

P2Y₁₄ receptor

Steroid receptors

Alicarboxylic acid receptors

Sensory receptors

Opsins

Rhodopsin

6FKB

Apoform: rhodopsin (apoform) (ID 720)

Complex: rhodopsin in complex with FYEGABNDKDAYPJ-UHFFFAOYSA-N (ID 721)

6FK8

Apoform: rhodopsin (apoform) (ID 840)

Complex: rhodopsin in complex with WRVOICVPIQQYTO-LIRRHRJNSA-N (ID 841)

6FK7

Apoform: rhodopsin (apoform) (ID 912)

Complex: rhodopsin in complex with GYIGPNZLXGKQBD-KUHUBIRLSA-N (ID 913)

2Z73

Apoform: rhodopsin (apoform) (ID 688)

Complex: rhodopsin in complex with Lysine-Retinol (ID 689)

6FK6

Apoform: rhodopsin (apoform) (ID 943)

Complex: rhodopsin in complex with UDAMUOKENMUCKG-FQEVSTJZSA-N (ID 944)

3C9L

Apoform: rhodopsin (apoform) (ID 900)

Complex: rhodopsin in complex with Lysine-Retinol (ID 901)

3C9M

Apoform: rhodopsin (apoform) (ID 756)

Complex: rhodopsin in complex with Lysine-Retinol (ID 757)

1U19

Apoform: Rhodopsin (ID 12)

3DQB

Apoform: Rhodopsin (ID 122)

5TE5

Apoform: rhodopsin (apoform) (ID 809)

Complex: rhodopsin in complex with QLEXUFWJSPRFOP-LCYNHIKNSA-N (ID 810)

6FKA

Apoform: rhodopsin (apoform) (ID 732)

Complex: rhodopsin in complex with QFUKMLGGPINITQ-FQEVSTJZSA-N (ID 733)

6FKC

Apoform: rhodopsin (apoform) (ID 706)

Complex: rhodopsin in complex with OHAKQPWAEANPAJ-QHCPKHFHSA-N (ID 707)

1GZM

Apoform: rhodopsin (apoform) (ID 894)

Complex: rhodopsin in complex with Lysine-Retinol (ID 895)

5TE3

Apoform: rhodopsin (apoform) (ID 750)

5DYS

Apoform: rhodopsin (apoform) (ID 872)

Complex: rhodopsin in complex with Lysine-Retinol (ID 873)

6FK9

Apoform: rhodopsin (apoform) (ID 777)

Complex: rhodopsin in complex with RWIUNGUJHWADDD-FQEVSTJZSA-N (ID 778)

3PQR

Apoform: Rhodopsin (ID 125)

OPN3

OPN4

OPN5

OPN1SW

OPN1MW

OPN1LW

Olfactory receptors

Orphan receptors

Class A orphans

GPR1

4XT1

Apoform: G-protein coupled receptor homolog US28 (ID 170)

4XT3

Apoform: g-protein coupled receptor homolog us28 (apoform) (ID 878)

Complex: g-protein coupled receptor homolog us28 in complex with fractalkine (ID 879)

GPR3

GPR4

GPR6

GPR12

GPR15

GPR17

GPR19

GPR20

GPR21

GPR22

GPR25

GPR26

GPR27

GPR31

GPR32

GPR33

GPR34

GPR35

GPR37

GPR37L1

GPR39

GPR45

GPR50

GPR52

GPR61

GPR62

GPR63

GPR65

GPR68

GPR75

GPR78

GPR79

GPR82

GPR83

GPR84

GPR85

GPR87

GPR88

GPR101

GPR132

GPR135

GPR139

GPR141

GPR142

GPR146

GPR148

GPR149

GPR150

GPR151

GPR152

GPR153

GPR160

GPR161

GPR162

GPR171

GPR173

GPR174

GPR176

GPR182

GPR183

LGR4

LGR5

LGR6

MAS1

MAS1L

MRGPRD

MRGPRE

MRGPRF

MRGPRG

MRGPRX1

MRGPRX2

MRGPRX3

MRGPRX4

P2RY8

P2RY10

TAAR2

TAAR3

TAAR4P

TAAR5

TAAR6

TAAR8

TAAR9

Other

Unclassified

US28

8F76

Complex: OR51E2 with propionate acid (ID 1245)

Complex: OR51E2-Q181D with propionate acid (ID 1246)

Complex: OR51E2 (ID 1244)

BILF1

Class B1 (Secretin)

Peptide receptors

Calcitonin receptors

Corticotropin-releasing factor receptors

CRF₁ receptor

4K5Y

Apoform: Corticotropin-releasing factor receptor 1 (ID 95)

Complex: Corticotropin-releasing factor receptor 1 in complex with CP-376395 (ID 97)

CRF₂ receptor

Glucagon receptor family

GHRH receptor

GIP receptor

GLP-1 receptor

6KK1

Apoform: glucagon-like peptide 1 receptor (apoform) (ID 704)

Complex: glucagon-like peptide 1 receptor in complex with MYZIDYJMNWEJMC-QHCPKHFHSA-N (ID 705)

5VEX

Apoform: glucagon-like peptide 1 receptor (apoform) (ID 710)

Complex: glucagon-like peptide 1 receptor in complex with PPTKULJUDJWTSA-UHFFFAOYSA-N (ID 711)

5NX2

Apoform: Glucagon-like peptide 1 (GLP-1) receptor (apoform) (ID 1061)

Complex: Glucagon-like peptide 1 (GLP-1) receptor in complex with truncated peptide agonist (ID 1065)

6KJV

Complex: glucagon-like peptide 1 receptor in complex with MYZIDYJMNWEJMC-QHCPKHFHSA-N (ID 1039)

Apoform: glucagon-like peptide 1 receptor (apoform) (ID 746)

5VEW

Apoform: glucagon-like peptide 1 receptor (apoform) (ID 698)

Complex: glucagon-like peptide 1 receptor in complex with MYZIDYJMNWEJMC-QHCPKHFHSA-N (ID 699)

6KK7

Apoform: glucagon-like peptide 1 receptor (apoform) (ID 876)

Complex: glucagon-like peptide 1 receptor in complex with MYZIDYJMNWEJMC-QHCPKHFHSA-N (ID 877)

GLP-2 receptor

glucagon receptor

5YQZ

Apoform: glucagon receptor (apoform) (ID 742)

Complex: glucagon receptor in complex with glucagon analogue (ID 743)

5EE7

Apoform: glucagon receptor (apoform) (ID 815)

Complex: glucagon receptor in complex with DNTVJEMGHBIUMW-IBGZPJMESA-N (ID 816)

4L6R

Apoform: Glucagon receptor (ID 110)

secretin receptor

Parathyroid hormone receptors

PTH1 receptor

6NBF

Complex: Parathyroid hormone receptor in complex with long-acting parathyroid hormone analog, mutant ML644-7 (ID 234)

Complex: Parathyroid hormone receptor in complex with parathyroid hormone analog, mutant ML643-73 (ID 237)

Complex: Parathyroid hormone receptor in complex with parathyroid hormone analog, mutant ML643-36 (ID 238)

Complex: Parathyroid hormone receptor in complex with parathyroid hormone analog (ID 247)

6FJ3

Apoform: parathyroid hormone/parathyroid hormone-related peptide receptor (apoform) (ID 755)

PTH2 receptor

VIP and PACAP receptors

Class B2 (Adhesion)

Class C (Glutamate)

Ion receptors

Amino acid receptors

GABA_B receptors

Metabotropic glutamate receptors

mGlu₁ receptor

4OR2

Apoform: Metabotropic glutamate receptor 1 (ID 81)

mGlu₂ receptor

mGlu₃ receptor

mGlu₄ receptor

mGlu₅ receptor

6FFH

Apoform: metabotropic glutamate receptor 5 (apoform) (ID 761)

Complex: metabotropic glutamate receptor 5 in complex with DWPQODZAOSWNHB-UHFFFAOYSA-N (ID 762)

4OO9

Apoform: Metabotropic glutamate receptor 5 (ID 74)

5CGD

Apoform: Metabotropic glutamate receptor 5 (ID 153)

Complex: Metabotropic glutamate receptor 5 in complex with HTL14242 (ID 193)

6FFI

Apoform: metabotropic glutamate receptor 5 (apoform) (ID 842)

Complex: metabotropic glutamate receptor 5 in complex with 2-[2-(3-methoxyphenyl)ethynyl]-6-methyl-pyridine (ID 843)

5CGC

Apoform: Metabotropic glutamate receptor 5 (ID 152)

mGlu₆ receptor

mGlu₇ receptor

mGlu₈ receptor

Sensory receptors

Orphan receptors

Class D1 (Ste2-like fungal pheromone)

Class F (Frizzled)

Protein receptors

Frizzled

FZD₁

FZD₂

FZD₃

FZD₄

FZD₅

FZD₆

FZD₇

FZD₈

FZD₉

FZD₁₀

SMO

6D35

Complex: smoothened in complex with CHOLESTEROL (ID 1134)

Apoform: smoothened (apoform) (ID 888)

5L7D

Apoform: Smoothened homolog (ID 161)

5L7I

Apoform: Smoothened homolog (ID 191)

Complex: Smoothened homolog in complex with Vismodegib (ID 192)

6D32

Apoform: smoothened (apoform) (ID 892)

Complex: smoothened in complex with Cyclopamine (ID 893)

4JKV

Apoform: smoothened homolog (apoform) (ID 791)

Complex: smoothened homolog in complex with SZBGQDXLNMELTB-UHFFFAOYSA-N (ID 792)

5V56

Apoform: smoothened homolog (apoform) (ID 823)

Complex: smoothened homolog in complex with ZDEZQXNVPSUJHK-UHFFFAOYSA-N (ID 824)

5V57

Apoform: smoothened homolog (apoform) (ID 740)

Complex: smoothened homolog in complex with ZDEZQXNVPSUJHK-UHFFFAOYSA-N (ID 741)

4N4W

Apoform: smoothened homolog (apoform) (ID 771)

Complex: smoothened homolog in complex with FOORCIAZMIWALX-JJIBRWJFSA-N (ID 772)

4O9R

Apoform: smoothened homolog/soluble cytochrome b562 chimeric protein (apoform) (ID 1022)

Complex: smoothened homolog/soluble cytochrome b562 chimeric protein in complex with Cyclopamine (ID 1023)

4QIM

Apoform: smoothened homolog/soluble cytochrome b562 chimeric protein (apoform) (ID 932)

Complex: smoothened homolog/soluble cytochrome b562 chimeric protein in complex with KSWYJUIFHPSZOL-UHFFFAOYSA-N (ID 933)

Class T (Taste 2)

Other GPCRs

Individual contributions

Class A (Rhodopsin)

Aminergic receptors

5-Hydroxytryptamine receptors

Acetylcholine receptors (muscarinic)

M₁ receptor

M₂ receptor

5ZKC

Apoform: M2 muscarinic acetylcholine receptor (ID 1121) - Brian Medel, IMIM

5YC8

Apoform: M2 muscarinic acetylcholine receptor (ID 1122) - Brian Medel, IMIM

M₃ receptor

5ZHP

Apoform: M3 muscarinic acetylcholine receptor (ID 1116) - Brian Medel, IMIM

M₄ receptor

M₅ receptor

Adrenoceptors

α_1A-adrenoceptor

α_1B-adrenoceptor

α_1D-adrenoceptor

α_2A-adrenoceptor

α_2B-adrenoceptor

α_2C-adrenoceptor

β₁-adrenoceptor

β₂-adrenoceptor

2R4R

Complex: Beta 2 Adrenergic Receptor & Carazolol (ID 6) - GPCR drug discovery group (Pompeu Fabra University)

Complex: Beta 2 adrenergic receptor and carazolol (ID 10) - GPCR drug discovery group (Pompeu Fabra University)

Complex: Beta 2 adrenergic receptor and isoproterenol (ID 9) - GPCR drug discovery group (Pompeu Fabra University)

β₃-adrenoceptor

Dopamine receptors

Histamine receptors

Trace amine receptors

Peptide receptors

Angiotensin receptors

Apelin receptors

apelin receptor

6KNM

Apoform: Apelin receptor (apoform) (ID 1041) - Francho Nerín-Fonz, IMIM

Complex: Apelin receptor in complex with single domain antibody JN241 (ID 1042) - Francho Nerín-Fonz, IMIM

Bombesin receptors

Bradykinin receptors

Cholecystokinin receptors

Complement peptide receptors

C3a receptor

C5a₁ receptor

6C1Q

Apoform: 6C1Q apoform (ID 1084) - Oriol Canal, Universitat Pompeu Fabra

6C1R

Apoform: 6C1R apoform (ID 1085) - Oriol Canal, Universitat Pompeu Fabra

C5a₂ receptor

Endothelin receptors

Formylpeptide receptors

FPR1

FPR2/ALX

6LW5

Apoform: 6LW5 apoform (ID 1082) - Oriol Canal, Universitat Pompeu Fabra

Complex: 6LW5 in complex with WKYMVm (ID 1081) - Oriol Canal, Universitat Pompeu Fabra

FPR3

Galanin receptors

Ghrelin receptors

Gonadotrophin-releasing hormone receptors

Kisspeptin receptors

Melanin-concentrating hormone

Melanocortin receptors

Motilin receptors

Neuromedin U receptors

Neuropeptide FF/neuropeptide AF receptors

Neuropeptide S receptors

Neuropeptide W/neuropeptide B receptors

Neuropeptide Y receptors

Neurotensin receptors

NTS₁ receptor

XXXX

Apoform: CaseStudy - FullAgonist (ID 1237) - Brian Medel, IMIM

Apoform: CaseStudy APO (ID 1236) - Brian Medel, IMIM

Complex: CaseStudy - InserveAgonist (ID 1238) - Brian Medel, IMIM

NTS₂ receptor

Opioid receptors

δ receptor

4N6H

Complex: Delta Opioid with Naltrindole (ID 4) - GPCR drug discovery group (Pompeu Fabra University)

Complex: delta opioid receptor (human) (ID 8) - GPCR drug discovery group (Pompeu Fabra University)

κ receptor

μ receptor

5C1M

Complex: Active mu-opioid receptor bound to the agonist morphine (ID 199) - Marta Filizola, Icahn School of Medicine at Mout Sinai

Complex: Mu-type opioid receptor bound to Oliceridine (ID 201) - Marta Filizola, Icahn School of Medicine at Mout Sinai

NOP receptor

Orexin receptors

Peptide P518 receptors

Prolactin-releasing peptide receptors

Proteinase-activated receptors

Relaxin family peptide receptors

Somatostatin receptors

Tachykinin receptors

Thyrotropin-releasing hormone receptors

Urotensin receptors

Vasopressin and oxytocin receptors

Protein receptors

Chemerin receptor

Chemokine receptors

CCR1

CCR2

CCR3

CCR4

CCR5

6AKY

Apoform: Chemokine Receptor CCR5 (ID 1119) - Brian Medel, IMIM

CCR6

CCR7

CCR8

CCR9

CCR10

CXCR1

CXCR2

CXCR3

CXCR4

CXCR5

CXCR6

CX₃CR1

XCR1

ACKR1

ACKR2

ACKR3

ACKR4

CCRL2

Glycoprotein hormone receptors

Prokineticin receptors

Lipid receptors

Free fatty acid receptors

Leukotriene receptors

Lysophospholipid (LPA) receptors

Lysophospholipid (S1P) receptors

Cannabinoid receptors

GPR18, GPR55 and GPR119

Platelet-activating factor receptors

Prostanoid receptors

DP₁ receptor

DP₂ receptor

EP₁ receptor

EP₂ receptor

EP₃ receptor

EP₄ receptor

FP receptor

IP receptor

TP receptor

6IIU

Apoform: Thromboxane A2 receptor (apoform) (ID 1043) - Francho Nerín-Fonz, IMIM

Complex: Thromboxane A2 receptor in complex with ramatroban (ID 1044) - Francho Nerín-Fonz, IMIM

6IIV

Apoform: Thromboxane A2 receptor (apoform) (ID 1075) - Francho Nerín-Fonz, IMIM

Complex: Thromboxane A2 receptor in complex with Daltroban (ID 1076) - Francho Nerín-Fonz, IMIM

Melatonin receptors

Nucleotide receptors

Adenosine receptors

A₁ receptor

A_2A receptor

5N2R

Apoform: A2A adenosine receptor A2AR-StaR2-bRIL (ID 1112) - Brian Medel, IMIM

3EML

Complex: A2a Adenosine receptor & Cholesterol (ID 7) - GPCR drug discovery group (Pompeu Fabra University)

A_2B receptor

A₃ receptor

P2Y receptors

Steroid receptors

Alicarboxylic acid receptors

Sensory receptors

Opsins

Rhodopsin

4J4Q

Apoform: active conformation of GPCR opsin stabilized by octylglucoside (ID 197) - George Khelashvili, Weill Cornell Medical College

OPN3

OPN4

OPN5

OPN1SW

OPN1MW

OPN1LW

Olfactory receptors

Orphan receptors

Other

Class B1 (Secretin)

Class B2 (Adhesion)

Class C (Glutamate)

Class D1 (Ste2-like fungal pheromone)

Class F (Frizzled)

Protein receptors

Frizzled

FZD₁

FZD₂

FZD₃

FZD₄

6BD4

Apoform: human apo-Frizzled4 receptor (ID 196) - Schulte lab, Karolinska Institutet

FZD₅

FZD₆

HOMO

Apoform: Frizzled-6 (ID 242) - Schulte lab, Karolinska Institutet

Apoform: Frizzled-6 (ID 243) - Schulte lab, Karolinska Institutet

Apoform: Frizzled-6 modeled from human Smoothened receptor (ID 241) - Schulte lab, Karolinska Institutet

Complex: active-like FZD6 SAG1.3-bound (ID 205) - Schulte lab, Karolinska Institutet

Complex: inactive FZD6 bound to Smoothened agonist (ID 202) - Schulte lab, Karolinska Institutet

FZD₇

FZD₈

FZD₉

FZD₁₀

SMO

4QIN

Apoform: human smoothened receptor (ID 198) - Schulte lab, Karolinska Institutet

Apoform: human smoothened receptor (ID 200) - Schulte lab, Karolinska Institutet

Complex: human smoothened receptor in complex with SAG (ID 203) - Schulte lab, Karolinska Institutet

Complex: human smoothened receptor in complex with SAG (ID 204) - Schulte lab, Karolinska Institutet

6OT0

Apoform: human Smoothened receptor (ID 239) - Schulte lab, Karolinska Institutet

Apoform: uman Smoothened receptor (ID 240) - Schulte lab, Karolinska Institutet

Class T (Taste 2)

Other GPCRs